Accelerate biotechnology

Meet the experts

    How important is matrix effect in analyzing bioprocess samples?
    Meet the Expert: Petra, Analytical Scientist The matrix effect is the effect on an analytical assay caused by all other components of the sample except the specific compound (analyte) to be analyzed. Matrix effects are observed either as a loss in response, resulting in an underestimation of the amount of analyte, or…

    Challenges in virus-based manufacturing in GMP
     Meet the Expert: Marije, GMP Scientist Many customers want to know how much time it will take to move a candidate viral vaccine or viral vector product from bench to bed. The next question often is what shortcuts can be taken to move even faster. Having strong preclinical data from in vivo…

    Analytical assay development: go ALL the way
    Meet the Expert: Gert, Analytical Assay Scientist The truth is; the accuracy and robustness of any process under development or manufacturing outcome is only as good as the reliability of the assays needed to understand the process. The effort involved to get to a comfortable situation where all necessary tests are available,…

    Latest advancements in bioprocess intensification for efficient biopharmaceutical production
    Meet the Expert: Ahd, Bioprocess Project Director Current costs of biopharmaceutical manufacturing often prevent segments of the world’s population from accessing critical medicines. Sometimes the costs even prevent medicines from being marketed. A significant part of these costs come from the need for large and expensive manufacturing facilities. Significant bioprocess intensification can…

    In manufacturing it’s ALL about Quality Control
    Meet the Expert: Caroline, Sr. Scientist Quality Control The Quality Control (QC) department performs analytical development, assay qualification, assay validation, testing on raw materials, cell substrates, virus seeds and cell banks. The department is also heavily involved in the in-process testing as well as testing the final drug substance and drug product.…

    Drivers in selecting a reliable partner for clinical GMP manufacturing
    Meet the Expert: Pim, GMP Scientist Clinical GMP manufacturing and release of biopharmaceutical products are two of the most sought-after outsourcing demands in life sciences. These activities are needed to allow subsequent testing in human subjects for safety and efficacy. Globally, the market for this outsourcing activity is estimated at about $3…

    Quality specialist is key in any biopharmaceutical development team
    Meet the Expert: Margreet, QA specialist The ability to translate biopharmaceutical research into products is known to have a high failure rate. A staggering 75% of published preclinical data cannot be reproduced or validated to allow further product development1. I believe that the only way to prevent such disappointments both scientifically, as…

    Novel HPLC assays allow for better biopharmaceutical development
    Meet the expert: Rinske, Associate Director Analytical Assays. HPLC assays have been widely used to analyze small molecules for decades. Now, HPLC is gaining momentum as an important tool for analysis of biopharmaceutical products. For example, after successfull introduction to analyze monoclonal antibodies, HPLC is increasingly used for large particle products like…

    How to scale your adherent cell culture
    Meet the expert: Matthijs, Associate Director Upstream Bioprocessing Cells derived from mammalian species and cultured under artificial laboratory conditions are used to produce complex biological products. As such cells normally grow as a tissue, most available artificial mammalian cells are originally surface-dependent. They are called adherent cells. Adherent cells will only duplicate…

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